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BPC-157 Arginate Class: Synthetic pentadecapeptide
Originally characterized by the Sikiric group at the University of Zagreb School of Medicine, BPC-157 is unusual among peptides for its reported oral activity attributed to its origin in gastric juice, which suggests evolutionary adaptation to the digestive environment
Mechanistic pathways identified in animal and in vitro work include: FAK-paxillin pathway activation: BPC-157 stimulates focal adhesion kinase (FAK) and its downstream effectors, promoting fibroblast migration and tendon cell outgrowth
Blood 2008;112: 2214-21 3
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