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Consistency with the protocol matters more than genetic luck in determining outcomes
Unlike semaglutide which solely activates GLP-1R (one of the three pivotal receptors regulating glucose homeostasis), tirzepatide also activates glucose-dependent insulinotropic polypeptide (GIP) receptor (GIPR) to enhance metabolic benefits with reduced side-effects 5
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Kariya C, Leitner H, Min E, van Heeckeren C, van Heeckeren A, Day BJ
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