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Eli Lilly's phase 3 program for retatrutide includes multiple trials across obesity, type 2 diabetes, and metabolic dysfunction-associated steatotic liver disease (MASLD)

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Antithrombotic Effects GLP-1 agonists reduce cardiovascular events through several mechanisms previously summarized to include improved glycemic control, weight loss, lowering blood pressure, lipid lowering, reduced atherogenesis, attenuated vascular inflammation, improved endothelial cell function, vasodilation, and direct cardiovascular protective effects [88, 89]