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Dehydration Frequent diarrhea or vomiting can lead to dehydration

It is also used to reduce the risk of major cardiovascular events (such as heart attack, stroke, and cardiovascular death) in adults with type 2 diabetes and established heart disease

doi: 10.1016/j.jhep.2021.10.013 45

The STEP 1 trial extension, published in Diabetes, Obesity and Metabolism , found participants regained two-thirds of their prior weight loss within a year of stopping semaglutide