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Children generally require weight-adjusted regimens, often 100 mcg monthly after initial loading
Normal B12 ranges typically fall between 200-900 pg/mL, though functional B12 status is better assessed by methylmalonic acid (MMA) and homocysteine levels
The debilitating fatigue which seems to be the most common symtpom of B12 deficiency may be due to a combination of neurological factors, anaemia, and the role of B12 in the mitochondria
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