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It functions as a coenzyme, mediating various reactions in energy production, and regulating processes like DNA repair, gene expression, and cellular responses to stress
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Flow cytometry using the DCFH-DA probe indicated that the marked elevation in ROS levels caused by the OGD and erastin treatments was rescued by the GSH treatment (Fig
We may speculate that this study provides an insight into how zinc sufficiency is important for BHMT functionality, since BHMT is a zinc dependent enzyme that catalyses the transmethylation of homocysteine to methionine in the presence of the methyl group donor betaine
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