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Through binding to the relaxin family peptide receptor 1 (RXFP1), this hormone elicits multiple physiological responses including vasodilation induction, reduction of inflammation and oxidative stress, and angiogenesis stimulation

216 Furthermore, a randomized, double-blind, placebo-controlled trial in 65 hemodialysis patients reported that taking 1,200 mg, but not 600 mg, of CoQ10 daily for four months decreased oxidative stress (as indicated by a decrease in F2-isoprostanes)

IV administration supports liver detoxification, enhances immune function, and promotes faster recovery from stress or physical exertion

Moreover, NAPstars are relatively large constructs, which may limit their targetability or usability in some subcellular locations, such as experienced for targeting Peredox to the mitochondrial matrix