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Diabetic retinopathy: Rapid improvement in blood glucose control, as may occur with potent glucose-lowering agents, has been associated with early worsening of diabetic retinopathy in people with pre-existing retinal disease (a class signal observed with semaglutide)
Paquin, A., Reyes-Moreno, C
Temporary worsening after GLP-1 RA initiation doesnt necessarily imply that GLP-1 RAs are harmful to the eye or should be discontinued
Compounding pharmacies assign their own beyond-use dates based on USP 797 guidelines, and those dates can range from 28 to 90 days when refrigerated, depending on the pharmacy and the specific formulation
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