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The 8-oxo-dG, an oxidative damage lesion biomarker, is higher in mtDNA than in nuclear DNA, attesting to associated oxidative damage [118]
This landscape illustrates both the promise and challenges: multiple valid targets exist, but translational failures have been common
C., Gallo, R
2 There is ongoing debate as to whether orally administered GSH is absorbed because it failed to raise plasma glutathione levels in some studies
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