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Hypothyroidism, even in its subclinical form, is associated with: Higher fasting insulin Increased HOMA-IR (a measure of insulin resistance) Elevated fasting glucose and hemoglobin A1C in some cases While GLP-1s can improve glycemic control, their effectiveness may be reduced in the presence of uncontrolled thyroid disease
Glucagon-like peptide-1: a potent regulator of food intake in humans Gut 1999 44 : 8186
Instead of initiating the pulse, it amplifies it
A randomized, Controlled trial of liraglutide for adolescents with obesity
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