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Ferroptosis, a term initially coined by Dixon in 2012, is a distinctive form of RCD featured by the iron-dependent lethal aggregation of lipid peroxides located at the cell membrane (4) ( Figure 1 )

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Pyridoxine (Vitamin B6) Pyridoxal 5-phosphate (PLP), the biologically active form of vitamin B6, is a coenzyme in the conversion of homocysteine to cysteine, which supports GSH biosynthesis [133]

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