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The oxidized form (GSSG) is like a drained battery that has already given its electron away and must be "recharged" by the body before it can be useful again
(This explains why hydroquinone has long been used for melasma removal , where brown or gray-brown patches of skin appear on foreheads, cheeks, chins and bridge of the nose.) In smaller doses (of at most 2%), hydroquinone can be purchased over-the-counter but pigment removal products with at least 4% hydroquinone concentration (considered to be the most effective concentration), require a prescription from a skin care specialist
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Simultaneous Fenton-like ion delivery and glutathione depletion by mno2-based nanoagent to enhance chemodynamic therapy
