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doi: 10.1016/j.bbi.2017.02.007 32 PrandovszkyEGaskellEMartinHDubeyJPWebsterJPMcConkeyGA

In PD, early GSH depletion in the substantia nigra precedes dopaminergic neuron loss, suggesting that redox dysfunction may be an inciting event that leads to eventual neuronal damage (Smeyne and Smeyne, 2013)