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Siemensma et al
Patients might ask their eyecare provider if the risk of vision loss from NAION outweighs the benefit of this GLP-1 drug use
However, there are few data on NRF2 activation in microglia in human tissues or animal models of ALS, and NRF2 signaling has not yet been evaluated in oligodendrocytes, although this may be relevant in the case of ALS which also involves demyelination [316]
Therefore, extensive future research is needed to address these issues and improve the delivery and patient experience [151, 190]
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