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Curr Opin Pharmacol (2016) 31:449
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GLP-1s, such as semaglutide (sold as Ozempic and Wegovy) and tirzepatide (sold as Mounjaro and Zepbound), are commonly used to treat Type 2 diabetes and obesity and can reduce cardiovascular and kidney disease risks, but researchers still are exploring potential risks of these medications
Researchers continue examining biological responses involving: Cellular energy utilization Fat storage Lipid metabolism Mitochondrial activity Nicotinamide recycling NAD+ metabolism Adipocyte biology By limiting NNMT activity, researchers investigate whether cells shift toward greater metabolic efficiency and altered fat metabolism
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