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The therapeutic window for inhibiting GGT as a cancer therapy is potentially large, as sustained inhibition of GGT activity did not induce any overt toxicities

Altered expression of 2-integrin, -catenin and genes associated with the Switch/Sucrose Non-Fermentable (SWI/SNF) complex further exacerbate these issues, creating an environment where bladder epithelial cells struggle to regenerate, thereby contributing to the persistent symptoms of IC (Park et al., 2024

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