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The Reed model provides a comprehensive mathematical representation of one-carbon GSH metabolism, boasting the inclusion of the transsulfuration pathway, as well as glutathione synthesis, transport and breakdown
However, another study showed the process of ferroptosis may exacerbate proteinuria, damaging renal tubules and promoting renal fibrosis via the HIF-1/HO-1 pathway in diabetes models
In the present study, the close association between GSTM2 knockout and hepatic steatosis was examined by using GSTM2 -null mice
TMEM206 plays a role in mediating acid-induced cell death as well as cell proliferation and migration, and its regulation is dependent on p53 through a p21-dependent mechanism (346)
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