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Detoxification: After exposure to toxins

In the longer-term (i.e., 4 weeks), intragastric administration of DB remained effective at increasing meal-induced GLP-1 secretion, associated with a reduction in body weight in obese mice, whereas another bitter tastant, quinine, had minimal effect on GLP-1 or ghrelin, despite reducing body weight (66)

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Retatrutide Led to Significant Blood Sugar and Weight Reductions The phase 3 clinical trial, called TRANSCEND-T2D-1, enrolled more than 500 adults with type 2 diabetes who were not able to manage their blood sugar with diet and exercise alone