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Weight loss from GLP-1s may ease those symptoms and support healthier testosterone levels through better rest

doi: 10.1002/14651858.CD004073.pub4 206 AgarwalASelvamMKPArafaMOkadaHHomaSKilleenAet al

Within this framework: HRT supports neural bioenergetics and mitochondrial stability, helping sustain adequate energy supply GLP-1 therapies reduce systemic and central inflammatory stress, improving the environment in which neurons function Rather than acting in isolation, these therapies may operate synergistically to stabilize both energy production and stress response systems within the brain

These are pharmacological observations from published research