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The FDA has ceased compounded tirzepatide following the stabilization of the national supply of GLP-1 medications, which includes tirzepatide
fumigatus (Vicentefranqueira et al., 2018, 2019), although the presence of two ZR-like motifs (i.e., Z inc R esponse consensus motifs) at 2000 and 1272 bp upstream the translation start codon (TSC) of metR and a ZR-like motif at 318 bp upstream the TSC of cysB indicates that a direct ZafA-mediated repression of these genes is possible