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Preliminary double-blind, placebo-controlled studies demonstrated the efficacy of melanotan in inducing penile erection in men with erectile dysfunction, although in a very restricted population.Unfortunately, there are no experimental data on the mode of action of melanotan II, as melanotan II is the first -MSH agonist inducing penile erection when injected peripherally
However, participants who had a history of, or met criteria for, conduct disorder, bipolar disorder, mania, or schizophrenia were excluded
PLoS Biol
Vitamin D is the most studied approach
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