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Cancer Res 1981
To analyze MRS data, we used the LCModel with a basis set of simulated spectra comprising the following 20 metabolites: Aspartate (Asp), phosphocholine (PCh), creatine (Cr), phosphocreatine (PCr), GABA, Gln, Glu, glutathione (GSH), glycine (Gly), mI, lactate (Lac), NAA, scyllo-inositol (Scyllo), taurine (Tau), glucose (Glc), N-acetylaspartylglutamate (NAAG), glycerophosphocholine (GPC), phosphorylethanolamine (PE), Serine (Ser), and MM (Fig
However, there are a few considerations: Digestive Discomfort : High doses (above 20 grams daily) may cause bloating, nausea, or stomach cramps in some people
Combined with secretory factors (SASP) from senescent cells induced locally by mitochondrial damage or endoplasmic reticulum stress, these elements collectively establish a pro-proliferative, anti-apoptotic inflammatory microenvironment
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