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Required tests typically include complete blood count, comprehensive metabolic panel, A1C, and kidney function markers

Gallbladder studies are indicated if these are suspected

doi: 10.1016/j.kint.2019.07.025 34 MoriYAjayAKChangJHMouSZhaoHKishiSet al

This dual mechanism of pharmacokinetic buildup plus physiological adaptation explains why many patients report progressive appetite reduction over their first 8 to 12 weeks