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Preparation of semaglutide long-acting injectable microcapsules with physicochemical properties, long-term stability, and pharmacokinetics and pharmacodynamics

Semaglutide (Wegovy) Injection is a prescription medicine used for weight management in adults who are overweight or living with obesity

At present, the gold standard management for the unsuccessful medical treatment of obesity is surgical intervention, providing unrivalled weight loss

Body weight and composition may theoretically influence distribution volume, but clinical studies have not demonstrated clinically significant differences in elimination based on body mass index or weight alone