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Since the headspace method allowed measuring the metabolism of odorants in mixtures, we tested if, as observed in drug metabolism, competitive metabolic interaction could arise between two distinct odorants, by modifying their relative perireceptor availability

1 In human tissues, the distribution of glutathione also shows significant organ specificity

Instead, it interacts with pathways that are already part of normal biology

This iron-sequestering capability is particularly important because excess free iron directly enters cells, concentrates in mitochondria, disrupts oxidative phosphorylation, catalyzes lipid peroxidation, and ultimately leads to cell death