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All variants were classified as pathogenic apart from c.527924_527914del, which has been classified as likely pathogenic

It is especially helpful for: Patients with dull skin, mild pigmentation, or post-acne dark marks Those looking for antioxidant support and detoxification benefits Individuals undergoing combination treatments for pigmentation However, I always emphasize a personalized treatment approach

But, drinking tea or coffee can lower iron absorption and should be avoided when taking iron supplements

Funding This work was supported by the China Agriculture Research System (CARS-41-G03) and National Natural Science Foundation of China (31401046)