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Further, galectin-1 upregulation aggravates the decreased sensitivity of HCC cells to sorafenib-induced ferroptosis by reducing lipid peroxidation
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However, it is crucial to emphasize that all data supporting this rationale derive from in vitro cell culture studies, in vivo animal experiments in rats and swine, and mechanistic extrapolation from established neuroendocrine physiology
[PubMed ID: 12600912]
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