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There are biochemical reasons that suggest an intramuscular (IM) injection delivers hydroxocobalamin to the bloodstream more rapidly and potentially more effectively than the subcutaneous (SC) route

Anemia, characterized by pale or jaundiced skin, is another potential sign, as vitamin deficiency can affect red blood cell production

Thus, a person who got a bariatric surgery such as gastric bypass surgery, and developed a B12 deficiency, can suffer from depression symptoms

Because research objectives vary between organizations, investigators may apply different methodologies depending on study design, project requirements, and analytical goals