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Identify potential risks early in development: Request a Forced Degradation Study Common Degradation Products Observed in GLP-1 Drugs LC-HRMS studies of semaglutide and liraglutide have shown that buffer composition, pH levels, and storage temperature can strongly influence degradation pathways
It scavenges free radicals, which can damage cells and DNA
Glavas, Sandra E
In addition, long-term use of Ozempic can affect kidney function in some individuals, particularly if they are experiencing gastrointestinal side effects that lead to dehydration
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