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Quite remarkably, in those with low POP levels, the typically robust association between diabetes and obesity was not observed in a nested case-controlled study, suggesting that obesity may exaggerate the metabolic disturbances caused by POPs (perhaps because adipose tissue provides a reservoir for fat-soluble toxins), rather than being directly responsible for the altered metabolism
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The antioxidant activity may be attributed to curcumin, the main polyphenol and active compound present in Curcuma longa which has the ability to increase the level of antioxidant enzymes, which include catalase, superoxide dismutase, and glutathione peroxidase (Panahi et al., 2012