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Nat Rev Mol Cell Biol 25(2):133155 Gammella E, Lomoriello IS, Conte A, Freddi S, Alberghini A, Poli M, Sigismund S et al (2021) Unconventional endocytosis and trafficking of transferrin receptor induced by iron
76 In turn, elevated glutamine consumption by cancer cells diminishes the glutamine supply necessary for T cells, consequently impeding the antitumor immune response
However, clinically relevant immunogenicity is relatively uncommon with most approved peptide drugs
& Higgins, J
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