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Insider Tip: Its important to note that, in 2020, the FDA restricted the sale of hydroquinone in over-the-counter products due to the ingredients potential to cause detrimental side effects.19 These include but arent limited to ochronosis (permanent gray or blue skin discoloration),20 thyroid disorders,21 and acute myeloid leukemias.22 If youre interested in a safer treatment for hyperpigmentation, Meladerm or one of the other options mentioned in our guide to whitening creams could be a good alternative
Zhu S, Zhang B, Wang Y, He Y, Qian G, Deng L, et al
Effect of metformin on all-cause and cardiovascular mortality in patients with coronary artery diseases: a systematic review and an updated meta-analysis
Global burden of blood-pressure-related disease, 2001
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