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If you have a history of B12 deficiency, malabsorption issues, or are vegetarian/vegan with marginal B12 status, the weekly B12 injection provides protection during the high-risk period of rapid weight loss

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After reviewing literature and conducting a two-round Delphi survey with 42 experts, a consensus emerged that emphasizes prioritizing clinical symptoms in diagnosis, with serum B12 as a screening marker supported by methylmalonic acid or homocysteine levels for additional confirmation

Following generation of the EH 2 a second NADPH binds and donates electrons generating the EH 4 form, which is competent for substrate reduction