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Life Sciences 51(13):1049-1056. [doi.org]
Anyone with a known copper allergy, open wounds or broken skin at the application area, or who is pregnant or breastfeeding
This is one reason head-to-head binding assays dont always match head-to-head secretion experiments and why researchers occasionally get surprised when GHRP-6 outperforms GHRP-2 in certain model contexts despite lower receptor binding affinity on paper
Understanding these differences helps contextualize why some users report local reactions and others report gastrointestinal ones
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