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However, more scientific proof is needed to further investigate its use
The first step is rate-limiting and subject to feedback inhibition by glutathione itself, holding intracellular concentrations in the low millimolar range, typically 1 to 8 mM (Griffith, Free Radical Biology and Medicine, 1999
Porkolb G, Mszros M, Tth A, Szecsk A, Harazin A, Szegletes Z, et al
Borchert A, Kalms J, Roth SR et al (2018) Crystal structure and functional characterization of selenocysteine-containing glutathione peroxidase 4 suggests an alternative mechanism of peroxide reduction
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