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Additionally, it was observed that GPE could improve the activity of endogenous antioxidant enzymes, up-regulate Nrf2/HO-1 pathway, and reduce lipid peroxidation (445)

Inhibiting this enzyme is examined in the literature for its effect on intracellular NAD availability, which is why the compound is frequently used as a research tool in NAD pathway studies rather than as a substitute for NAD itself

doi: 10.1016/j.imlet.2022.02.007 199 DeyhleMRCarlisleMSorensenJRHafenPSJespersonKAhmadiMet al