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Epub 2011 Jun 22
Long half-life (characterized in studies): Reported as long-acting in preclinical and clinical research, supporting extended-interval dosing within those study protocols
In summary, the mechanistic picture suggests GLP-1 RAs could improve the fertile milieu by aiding weight loss and reducing metabolic inhibitors of fertility, and they may even directly improve certain sperm functions, but they are not magic bullets for restoring testosterone in severely obese or diabetic states (at least in isolation)
Even a little psychological support while youre receiving treatment helps in the long run
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