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What the Pivotal Trial Actually Measured STEP 1 enrolled 1,961 adults with a body mass index of 30 or greater, or 27 or greater with at least one weight-related coexisting condition, none of whom had diabetes
Semaglutide, on the other hand, is a GLP-1 medication
Increased lipase and alanine aminotransferase were noted in 3 (23.1%) and 1 (7.7%) of the patients, respectively, with none of those resulting in pancreatitis and/or cholelithiasis
Gastrointestinal reactions in this class occur predominantly during dose escalation, which is to say during the early months
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