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Eryptosis, analogous to apoptosis in nucleated cells, is a physiological process that eliminates senescent or defective erythrocytes before hemolysis occurs, thereby preventing toxicity resulting from the release of hemoglobin into the bloodstream

Failure rate of isolated medial meniscus repair in the stable knee: Systematic review and meta-analysis

However, a major limitation of macrophage-reprogramming strategies lies in the extreme plasticity of TAMs and high tumor heterogeneity, which can cause reprogrammed M1 macrophages to revert to an M2 state