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Baseline Laboratory Assessment Before initiating GHK-Cu therapy, obtain: Serum copper level (normal range: 70 to 140 mcg/dL) Ceruloplasmin (normal range: 20 to 35 mg/dL) 24-hour urine copper (to exclude copper overload states) Hepatic function panel (AST, ALT, alkaline phosphatase, total bilirubin) Complete blood count with differential Wound photography and planimetric measurement (length, width, area) Wound culture if signs of infection are present Patients with Wilson disease, known copper storage disorders, or hepatic cirrhosis should not receive exogenous copper peptides [13]
Endothelial cells seeded on a three-dimensional matrix (Matrigel) are able to form capillary-like structures
The cell index was defined as R n -R b at each time point of measurement, where R n is the cell-electrode impedance of the well when it contains cells, and R b is the background impedance of the well with the medium alone
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