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Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension
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Histidine-based tag for a total length of 99 a.a The recombinant protein migrates with an apparent molecular mass of 12.5 kDa in SDS-PAGE
Regular thyroid function tests (TSH and free T4) are recommended during treatment, particularly if significant weight loss occurs
Nausea, the most commonly reported side effect, typically peaks during dose escalation and then subsides within 1 to 2 weeks at the new dose level
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