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The evidence base for B12 supplementation is stronger than for L-carnitine in the context of GLP-1 medications, at least in terms of addressing a documented risk (B12 deficiency during prolonged GLP-1 use)

Tendon Injuries Tendon injuries are among the most common reasons active individuals experience persistent knee pain

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Given the intractable pediatric obesity epidemic and associated rise in type 2 diabetes in youth, made worse by the COVID-19 pandemic related shutdowns and disruptions in opportunities for exercise and play in youth, this new class of medications will certainly benefit children with morbid obesity and type 2 diabetes