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The progression from single to dual to triple agonism has produced measurable advances in clinical research outcomes, and the category continues to evolve as additional compounds enter clinical development
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Chem Res Toxicol 21:117128 Jordan A, Haidacher S, Hanel G, Hartungen E, Herbig J, Maerk L, Schottkowsky R, Seehauser H, Sulzer P, Maerk TD (2009) An online ultra-high sensitivity proton-transfer-reaction mass-spectrometer combined with switchable reagent ion capability (PTR+SRI-MS)
Male C57BL/6 and leptin-deficient ob/ob mice (with exons 2 and 3 of the leptin gene deleted) were obtained from Biocytogen Pharmaceuticals (Beijing, China)
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