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This oxidative damage activates signaling pathways that promote inflammation and fibrosis, leading to glomerular hypertrophy, mesangial expansion, and tubulointerstitial fibrosis [183]
Methods Patients with a breast cancer diagnosis were prescribed GLP-1 RAs from January 1, 2015, to December 31, 2023, at Memorial Sloan Kettering Cancer Center in New York, New York, with follow-up weight data (before and during treatment with a GLP-1 RA) included in this retrospective cohort
The Bottom Line The appeal of needle-free GLP-1 options is understandable, but the current evidence does not support sublingual semaglutide drops or weight loss patches as effective alternatives to proven treatments
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