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doi:10.1002/oby.24067
It's a really promising candidate (see below), but while reading all the goodness about it in a minute, do not forget that derivatives not only have to be absorbed into the skin but also have to be converted to pure vitamin C (ascorbic acid or AA) and the efficacy of the conversion is often unknown
Your mast cells are overreacting, and your histamine breakdown system is overwhelmed
This receptor interaction triggers intracellular signalling cascades, primarily the PI3K-AKT and MAPK pathways (1)
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