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S., Xu, S., Graeber, T
Although GLP-1 medications have transformed obesity treatment, there remains a significant need for rigorous data examining how these therapies affect fertility and reproductive function in this population. The RESTORE study is currently evaluating semaglutide treatment in girls and women with PMOS and obesity, with the overarching goal of determining whether weight loss and metabolic improvements can restore ovulation and improve reproductive outcomes
A 2022 systematic review found that omega-3 supplementation or dietary intake was associated with improved oocyte quality in women undergoing ART, evaluated by both morphological and morphokinetic parameters. Animal studies show that omega-3 rich diets prolong reproductive lifespan and improve oocyte mitochondrial dynamics. Good dietary sources include oily fish (salmon, mackerel, sardines), walnuts, chia seeds, and flaxseeds
You may need to take another pill or use backup contraception (9,10)
