Two grams (2,000 milligrams) seems to be the sweet spot for long-term effectiveness without health risks
Preclinical studies have confirmed that GLP-1RAs can significantly reduce body fat accumulation and improve insulin sensitivity, which provides a new potential strategy for the treatment of sarcopenia [12]
2, the meta-analysis of all available cohorts showed a significant reduction in risk for schizophrenia (OR = 0.72, 95% CI [0.610.86]), bipolar disorder (OR = 0.91, 95% CI [0.880.94]), bulimia nervosa (OR = 0.34, 95% CI [0.230.52]), PTSD (OR = 0.45, 95% CI [0.310.67]), and autism (OR = 0.55, 95% CI [0.320.93])
That means the highest drug concentration during the week is about 2.7 times the lowest concentration