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when glutathione falls below approximately 30% of normal, NAPQI covalently binds hepatocyte proteins, causing necrosis
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TB-500 is a synthetic peptide based on a fragment of Thymosin Beta-4 (TB-4), a naturally occurring protein found in nearly all human and animal cells
For example, due to a genetic mutation that inhibits the synthesis of glutathione starting from its enzyme glutathione synthetase
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