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Two oral GLP-1s reached approval in the last six months

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Pg , Fn , and Sm groups exhibited a downregulation in FMO2 gene expression compared to the control group, which potentially indicates a general stress response of the liver to oral pathogenic bacterial infection ( In vitro TMAO exacerbates lipid accumulation, inflammation, and fibrosis in the liver ( in vitro ( Pg orally exhibited hepatic steatosis, accompanied by increased expression levels of lipid metabolism factors

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