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This event could then prime activation of integrin signaling, a possibility supported by our observation that active v3 integrin is found in the podosomes of THP-1 cells only after 25HC treatment and 25HC promotes activation of v3 integrin in FAs of A549 cells
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Overwhelming oxidative stress : During acute injury, inflammation, or toxic exposure, the oxidative burden may exceed the capacity of enzymatic antioxidants
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